The stage is set for the 2025/26 CAF Champions League Round of 32, with Africa’s finest clubs ready to clash in two-legged encounters scheduled between October 17–19 (first leg) and October 24–26 (return leg).

Fans across the continent are buzzing as the draw threw up some intriguing ties. Uganda’s Vipers SC, fresh from eliminating African Stars, will lock horns with Zambia’s Power Dynamos, who stunned Ivorian giants ASEC Mimosas.

Defending champions Pyramids FC of Egypt begin their title defense against Rwanda’s APR, with the winner facing Ethiopia’s Ethiopian Insurance, the club boasting Ugandan forward Allan Kayiwa.

Elsewhere, South African legend Denis Onyango’s Mamelodi Sundowns meet Nigeria’s high-flying Remo Stars, while Al Ahly, the record title holders, take on Burundi’s spirited Aigle Noir.

East Africa will also be buzzing as Tanzania’s giants Young Africans and Simba SC face Silver Strikers (Malawi) and Nsingizini Hotspurs (Eswatini) respectively.

Other mouthwatering fixtures include Rivers United (Nigeria) against Black Bulls (Mozambique), AS FAR (Morocco) squaring off with Horoya (Guinea), and a potential blockbuster between Orlando Pirates (South Africa) and the winner of St. Eloi Lupopo (DR Congo) vs. Al Merriekh (Sudan).

The winners over two legs will secure passage to the group stages, where the stakes—and rewards—rise even higher.Full CAF CL Round of 32 Fixtures

Remo Stars (Nigeria) vs Mamelodi Sundowns (RSA)

Vipers (Uganda) vs Power Dynamos (Zambia)

Aigle Noir (Burundi) vs Al Ahly (Egypt)

Silver Strikers (Malawi) vs Young Africans (Tanzania)

Stade d’Abidjan (Ivory Coast) vs Petro de Luanda (Angola)

Horoya (Guinea) vs AS FAR (Morocco)

Nsingizini Hotspurs (Eswatini) vs Simba (Tanzania)

Rahimo (Burkina Faso) vs Esperance (Tunisia)

Black Bulls (Mozambique) vs Rivers United (Nigeria)

Police FC (Kenya) vs Al Hilal (Sudan)

Colombe (Cameroon) vs MC Alger (Algeria)

FC Nouadhibou (Mauritania) vs Stade Malien (Mali)

US Monastir (Tunisia) vs JS Kabylie (Algeria)

St. Eloi Lupopo (DR Congo)/Al Merriekh (Sudan) vs Orlando Pirates (RSA)

Ethiopian Insurance (Ethiopia) vs APR (Rwanda)/Pyramids (Egypt)